De Soto, Missouri is a city in Jefferson County, established in 1857 and named after the Spanish explorer Hernando de Soto. It was incorporated in 1869 and has a rich history in coal mining. The city is home to the Jesse James Wax Museum, a notable attraction that offers insights into the life and times of the famous outlaw. De Soto's population is approximately 6,400 as of the latest census.
De Soto, MO has 1 Ace Hardware location. The city also has:
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