Old Appleton, MO, US is a small village in Cape Girardeau County, established in the mid-19th century. It was named after a local family and served as a stop on the St. Louis Iron Mountain and Southern Railway. The village has a rich agricultural history, with many of its residents involved in farming. The Old Appleton Log Cabin, a well-preserved example of early pioneer life, is a notable attraction, offering a glimpse into the past for visitors.
Old Appleton, MO has 1 Dollar General location.
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