Prairie Home is a small town in Missouri, US, with a population of approximately 300 as of the 2020 census. It is located in Cooper County, in the central part of the state. The town was established in the mid-19th century and was named after the surrounding prairie landscape. Prairie Home is home to the historic Lindley House, a Greek Revival-style home built in 1856, which is listed on the National Register of Historic Places. The town is also known for its annual Prairie Home Fair, a celebration of the community's agricultural heritage.
Prairie Home, MO has 1 Dollar General location.
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