Pamplico is a town in Florence County, South Carolina, United States, with a population of approximately 1,200 as of 2019. It was incorporated in 1896 and named after the nearby Pee Dee River, which was originally called the Pamplico River. The town has a rich history in agriculture, particularly in cotton and tobacco farming. A notable attraction in Pamplico is the Hopewell Presbyterian Church, which was built in 1787 and is one of the oldest churches in the state.
Pamplico, SC has 1 Dollar General location.
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