Picayune is a city located in Pearl River County, Mississippi, US. It was incorporated in 1904 and has a population of approximately 11,000 as of 2020. The city is known for its historic downtown district and the Crosby Arboretum, a 104-acre native plant conservatory and educational facility. Picayune was named after a local newspaper, The Picayune, which was founded in 1869. The city has a rich history in the lumber industry and was once home to several sawmills.
Picayune, MS has 1 Home Depot location. The city also has:
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