De Soto, Illinois is a village located in Jackson County, in the southern part of the state. It was incorporated in 1874 and has a population of approximately 1,600 residents as of the 2020 census. The town is named after the Spanish explorer Hernando de Soto. De Soto is home to the historic De Soto Railroad Depot, which was built in 1877 and is now listed on the National Register of Historic Places. The depot serves as a museum and community center, showcasing the town's rich history and railroad heritage.
Dollar General takes the top spot among Dollar Stores and Deep Discount Stores in De Soto, Illinois with 1 locations as of April 12, 2024.