De Soto, Missouri is a city in Jefferson County, established in 1857 and named after the Spanish explorer Hernando de Soto. It was incorporated in 1869 and has a rich history in coal mining. The city is home to the Jesse James Wax Museum, a notable attraction that offers insights into the life and times of the famous outlaw. De Soto's population is approximately 6,400 as of the latest census.
Ace Hardware takes the top spot among Home Improvement Stores in De Soto, Missouri with 1 locations as of May 8, 2024. True Value is in second place with 1 locations.