Sikeston is a city in the southeastern corner of Missouri, US, located in Scott County. It was founded in 1860 and incorporated in 1874, with a current population of approximately 16,000. The city is known for its agricultural industry, particularly cotton and soybeans. A notable landmark is the historic Sikeston Depot, which was built in 1916 and served as a passenger and freight station for the Missouri Pacific Railroad until the 1960s.
Lowe's takes the top spot among Home Improvement Stores in Sikeston, Missouri with 1 locations as of May 11, 2024.