Pamplico is a town in Florence County, South Carolina, United States, with a population of approximately 1,200 as of 2019. It was incorporated in 1896 and named after the nearby Pee Dee River, which was originally called the Pamplico River. The town has a rich history in agriculture, particularly in cotton and tobacco farming. A notable attraction in Pamplico is the Hopewell Presbyterian Church, which was built in 1787 and is one of the oldest churches in the state.
Dollar General takes the top spot among Dollar Stores and Deep Discount Stores in Pamplico, South Carolina with 1 locations as of April 12, 2024.